Her breakthrough came with TVB drama ‘Return of the Cuckoo’ which was followed by other notable series like ‘Beyond the Realm of Conscience’, ‘Line Walker’, ‘Can't Buy Me Love’ and ‘Maidens’ Vow’.
The latter earned her Best Actress Award and My Favourite Female TV Character award at the TVB Anniversary Awards in 2006, making her the first TVB actress to earn two major awards in the same year in the event’s history.
The early stage of her career was often characterised by her coy, squeaky voice and criticisms of her acting skills.However, Charmaine overcame these problems and made her breakthrough in Return of the Cuckoo in 2000, co-starring with Nancy Sit, Julian Cheung and Steven Ma.In 2011 she was awarded Best Actress at the Asian Television Awards for her performance in Can't Buy Me Love.After 14 years, she left TVB to develop her acting career in China and return in 2014 for a two-year contract with TVBC, a joint venture between TVB and China Media Capital (CMC) and Shanghai Media Group (SMG).She also won the Top Four Actresses Award with Ruby Lin, Zhao Wei and Liu Yifei.
Charmaine was the first Hong Kong television actress to be shortlisted for the semi-finals of the Best Actress category at the 35th International Emmy Awards in 2007.
Hong Kong media outlets have pointed to his age as the reason for this change, speculating that he is finally ready to settle down and get married.
However, Chan, who joined TVB as an actress after winning the Miss Hong Kong beauty pageant in 2013, says marriage is not on the cards just yet.
A graduate from the International Hotel Management Institute Switzerland, she took part in the 1997 Miss Hong Kong Pageant and finished as second runner-up following which she was signed under TVB, the first wireless commercial TV station in her homeland.
Although initially she drew criticism for her acting skills, with time she developed and honed her skills to emerge as one of the revered actresses both in homeland and overseas.
Line Walker is her first series since her return, where Charmaine portrays as an undercover cop and was highly praised for her role as "Ding Siu Ka" (丁小嘉).